Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI10F9H3), TrueMAB
Human KLK8 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(Paraffin)에서 검증됨. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 암 및 질환 바이오마커 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10F9H3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
The KLK8 gene is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may participate in proteolytic cascades in the skin and serve as a biomarker for ovarian cancer.
Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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