Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI13D9), TrueMAB
Human KLK8 단백질(아미노산 33-260)을 항원으로 한 Mouse monoclonal antibody. Western blot에 1:2,000 희석으로 사용 가능. Lyophilized 형태로 제공되며, PBS(pH 7.3, 8% trehalose)에 용해. KLK8 관련 암 및 질환 연구용.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases involved in diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
The KLK8 gene, one of fifteen kallikrein subfamily members on chromosome 19, is believed to participate in proteolytic cascades in the skin and may serve as a biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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