Thermo Fisher Scientific OPRD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-372 of human OPRD1 (NP_0009023) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OPRD1,uniProtId:P41143-1,ncbiNodeId:9606,antigenRange:300-372,antigenLength:372,antigenImageFileName:PA5-121199_OPRD1_P41143-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121199_OPRD1_P41143-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.59 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914771

Product Specific Information

Positive test controls include: Mouse brain, Rat brain. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein.

Immunogen sequence: LHLCIALGYA NSSLNPVLYA FLDENFKRCF RQLCRKPCGR PDPSSFSRAR EATARERVTA CTPSDGPGGG AAA

Target Information

OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimers patients and in the putamen in Parkinsons disease.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.