Thermo Fisher Scientific HK3 Polyclonal Antibody
HK3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 0.83 mg/mL 농도, 안정적 PBS/glycerol buffer 보존.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–270 of human HK3 (NP_002106.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914769 |
Product Specific Information
Positive test controls include: HepG2, HL-60, THP-1, NCI-H460, Mouse liver.
Immunogen sequence:
MDSIGSSGLR QGEETLSCSE EGLPGPSDSS ELVQECLQQF KVTRAQLQQI QASLLGSMEQ ALRGQASPAP AVRMLPTYVG STPHGTEQGD FVVLELGATG ASLRVLWVTL TGIEGHRVEP RSQEFVIPQE VMLGAGQQLF DFAAHCLSEF LDAQPVNKQG LQLGFSFSFP CHQTGLDRST LISWTKGFRC SGVEGQDVVQ LLRDAIRRQG AYNIDVVAVV NDTVGTMMGC EPGVRPCEVG LVVDTGTNAC YMEEARHVAV LDEDRGRVCV
Target Information
Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway.
In vertebrates, there are four major glucose phosphorylating isoenzymes: hexokinase I, II, III, and IV (glucokinase).
Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6-phosphate.
The catalytic activity of hexokinase III is associated with the C terminus, while regulatory function is associated with the N terminus.
Note: For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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