Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (rGH/1450)
인체 성장호르몬(GH)을 표지하는 단클론 항체로, IHC(P) 및 IHC(PFA) 실험에 적합합니다. Mouse IgG1, kappa 아이소타입이며, Protein A/G로 정제된 액상 형태입니다. 4°C 보관, 동결 금지. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rGH/1450 |
| Immunogen | Recombinant fragment (aa 58–187) of human Growth Hormone (GH) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
The GH1 gene, along with four related genes, is located at the growth hormone locus on chromosome 17, sharing a high degree of sequence identity.
Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
hGH is produced by somatotroph cells in the pituitary gland and acts through cytokine receptor subfamily membrane receptors.
Its major function is to stimulate body growth by inducing the liver and other tissues to secrete IGF-1, promoting myoblast differentiation and proliferation, and enhancing amino acid uptake and protein synthesis in muscles and other tissues.
Mutations or deletions in the GH1 gene can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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