Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (GH/1450)
인간 성장호르몬(GH)을 표적하는 단클론 항체로, 뇌하수체 마커 연구에 적합합니다. IHC(P) 및 IHC(PFA) 실험에 사용 가능하며, 고순도 Protein A/G 정제 제품입니다. PBS(pH 7.4) 완충액에 보존되어 있으며 방부제 무첨가 상태로 제공됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GH/1450 |
| Immunogen | A recombinant fragment (around aa58–187) of human Growth Hormone (GH) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play a critical role in growth control.
The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17, sharing a high degree of sequence identity.
Alternative splicing results in five isoforms (19–24 kDa). hGH is produced by somatotroph cells in the pituitary gland and acts through cytokine receptor subfamily membrane receptors.
Its main function is to stimulate the liver and other tissues to secrete IGF-1, promoting myoblast differentiation and proliferation, as well as amino acid uptake and protein synthesis in muscle and other tissues.
Mutations or deletions in the GH1 gene can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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