Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (SPM106)
Pituitary marker로 사용되는 Growth Hormone 단일클론 항체로, 인간 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, Protein A/G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM106 |
| Immunogen | Recombinant fragment (around aa58–187) of human Growth Hormone (GH) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17. These genes share a remarkably high degree of sequence identity. Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
HGH is produced by the somatotroph cells in the pituitary and acts through binding to membrane receptors of the cytokine receptor subfamily. Its major role in stimulating body growth is to promote secretion of IGF-1 from the liver and other tissues. It stimulates differentiation and proliferation of myoblasts and enhances amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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