Thermo Fisher Scientific TCR gamma/delta Monoclonal Antibody (UC7-13D5), Biotin, eBioscience
마우스 TCR γδ 복합체를 인식하는 UC7-13D5 단클론 항체로, Flow Cytometry에 최적화된 Biotin 결합 항체입니다. 면역조절 및 감염 연구에 유용하며, 0.5 µg/test 농도로 사용 권장됩니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 0.5 µg/test |
| Miscellaneous PubMed (Misc) | - |
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Recommended Isotype Control | Armenian Hamster IgG Isotype Control (eBio299Arm), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UC7-13D5 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_466684 |
| Filtration | 0.2 µm post-manufacturing filtered |
Additional Formats:
Product Specific Information
The UC7-13D5 monoclonal antibody reacts with the mouse gamma delta TCR complex. Gamma delta TCR is expressed by a small subset of T cells in the thymus, peripheral lymphoid tissues, intestinal epithelium, and epidermis. These cells are suggested to recognize bacterial ligands and some tumor cells in the context of MHC class I-like gene products and play roles in immune regulation and bacterial infection responses.
Applications Reported:
UC7-13D5 is used as a phenotypic marker for gamma delta TCR-expressing T cells in flow cytometric analysis.
Applications Tested:
Tested by flow cytometric analysis of mouse thymocytes and splenocytes. Recommended usage ≤ 0.5 µg per test (in 100 µL final volume). Optimal antibody concentration should be titrated for specific assay conditions. Typical cell number range: 10⁵–10⁸ cells/test.
Target Information
TCR gamma/delta (T-cell receptor gamma/delta) are specialized T cells involved in immune recognition. TCRs discriminate foreign from self-peptides presented by MHC class II molecules, critical for adaptive immunity. Gamma delta T cells are mainly found in epithelial tissues, showing limited TCR diversity and distinct antigen recognition compared to alpha-beta T cells. Subsets of gamma delta T cells exhibit antitumor and immunoregulatory activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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