Thermo Fisher Scientific HTR5A Polyclonal Antibody
Thermo Fisher Scientific의 HTR5A 폴리클로날 항체는 인간 5-HT5A 수용체를 인식하며, IHC(P) 및 ELISA에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from N-terminus of human 5HT5A Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550329 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%); Monkey (94%); Marmoset (88%) - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) is involved in various psychiatric conditions and has vasoconstrictive and vasodilatory effects.
The HTR5A gene encodes a multi-pass membrane protein functioning as a receptor for serotonin (5-HT) and couples to G-proteins.
This receptor contributes to intracellular Ca²⁺ mobilization regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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