Thermo Fisher Scientific Oncostatin M Polyclonal Antibody
인간 Oncostatin M에 특이적인 염소 다클론 항체로, WB·Flow·Neutralization 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 보존제 무첨가 PBS/trehalose 완충액에 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | - |
| Flow Cytometry (Flow) | 2.5 µg per million cells | - |
| Neutralization (Neu) | 0.02–0.04 µg/mL | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Oncostatin M (Ala26–Arg221) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609440 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Endotoxin level < 0.10 EU per 1 µg of antibody (LAL method).
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in neurogenesis, osteogenesis, and hematopoiesis. Produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates fibroblast, smooth muscle, and Kaposi’s sarcoma cell proliferation, while inhibiting growth of certain normal and tumor cell lines. OSM also promotes cytokine release (IL-6, GM-CSF, G-CSF) from endothelial cells and enhances LDL receptor expression in hepatoma cells. It shares structural and functional similarities with LIF, IL-6, and CNTF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-47002_Oncostatin_M_P13725-1_Goat.svg, PA5-47002_Oncostatin_M_P13725-1_Goat_PDP.jpeg)
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