Thermo Fisher Scientific CXCL10 Polyclonal Antibody
CXCL10 단백질을 인식하는 염소 유래 다클론 항체로, IHC, ICC/IF, Flow Cytometry, ELISA, Neutralization 등 다양한 응용에 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 보존제 무첨가.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
| ELISA (ELISA) | Assay-Dependent |
| Neutralization (Neu) | 1–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human CXCL10/IP-10/CRG-2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609777 |
Product Specific Information
- In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse CRG-2, recombinant human (rh) MIG, and rhGRO gamma.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.20 EU per 1 µg of the antibody by the LAL method.
Target Information
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985.
The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include:
- Stimulation of monocytes, natural killer, and T-cell migration
- Regulation of T-cell and bone marrow progenitor maturation
- Modulation of adhesion molecule expression
- Inhibition of angiogenesis
Mig and IP-10 share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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