Thermo Fisher Scientific CXCL10 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse CRG-2, recombinant human (rh) MIG, and rhGRO gamma.
• Reconstitute at 0.2 mg/mL in sterile PBS.
• Endotoxin level is <0.20 EU per 1 µg of the antibody by the LAL method.

Target Information

IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985.
The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include:

• Stimulation of monocytes, natural killer, and T-cell migration
• Regulation of T-cell and bone marrow progenitor maturation
• Modulation of adhesion molecule expression
• Inhibition of angiogenesis

Mig and IP-10 share the same receptor, CXCR3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.