Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI1E6), TrueMAB
인간 ESRRA 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. PBS 완충액에 8% 트레할로스를 포함하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB)
Tested dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–205 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. ERR family members share a highly conserved DNA-binding domain with 68% identity to the estrogen receptor. ERRα binds to the ERRα response element (ERRE) containing a consensus half-site (5'-tnaaggtca-3') and can also bind to the medium-chain acyl-CoA dehydrogenase (MCAD) response element NRRE-1. It functions as a metabolic regulator and is predominantly expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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