Thermo Fisher Scientific Neuritin Polyclonal Antibody
Neuritin 단백질을 검출하기 위한 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합하며 인간 및 마우스 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 2-8°C 보관 가능. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–10 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 20 amino acid peptide from near the center of human neuritin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156171 |
Product Specific Information
- Suggested positive control: Daudi cell lysate
- PA5-20368 can be used with blocking peptide PEP-0482
Target Information
Neuritin belongs to the neuritin family and is expressed in postmitotic-differentiating neurons of the developing nervous system as well as neuronal structures associated with plasticity in adults. Its expression can be induced by neural activity and neurotrophins. The protein contains a consensus cleavage signal found in glycosylphosphatidylinositol (GPI)-anchored proteins and promotes neurite outgrowth and arborization, indicating its role in promoting neuritogenesis. Overexpression of the protein may be associated with astrocytoma progression. Alternative splicing leads to multiple transcript variants. NRN1 is associated with Severe Congenital Neutropenia 8 and Spinal Muscular Atrophy, Type III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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