
Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI4G3), TrueMAB
인간 NME1 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot과 IHC(P) 적용 가능. 정제된 무보존제 항체로 재조합 NME1 단백질을 면역원으로 사용. 연구용으로만 사용되며, 안정적인 동결건조 형태로 제공.
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Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI4G3), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G3 |
| Immunogen | Full length human recombinant protein of human NME1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NME1 is associated with reduced mRNA levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) forms a hexamer composed of isoforms A (NME1) and B (NME2).
Mutations in NME1 are linked to aggressive neuroblastomas. Two transcript variants exist, encoding different isoforms.
Co-transcription with NME2 generates naturally occurring NME1-NME2 fusion transcripts that combine sequences from both genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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