
Thermo Fisher Scientific MUC16 Monoclonal Antibody (OTI2C4), TrueMAB
인간 MUC16(CA125) 단백질을 인식하는 단클론 항체로, Western blot에 최적화됨. Mouse IgG1 아이소타입이며 비결합형 상태로 제공. 동결건조 형태로 PBS(8% trehalose) 완충액에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 10329–10628 of human MUC16 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CA125 determinant is present on a high molecular weight mucin-like glycoprotein. It is expressed in tissues derived from coelomic and Müllerian epithelium such as amnion, pleura, pericardium, and peritoneum. In adult tissues, it is found in epithelial cells of the fallopian tube, endometrium, endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland, as well as in the mesothelial lining of pleura, pericardium, and peritoneum.
CA125 expression is also observed in ovarian tumors of serous, endometrioid, or clear cell types and in adenocarcinomas of Müllerian origin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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