Thermo Fisher Scientific HEY1 Monoclonal Antibody (3B4)
HEY1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal antibody(3B4). Western blot 및 ELISA에 적합하며, Notch 신호전달 관련 연구에 유용. PBS(pH 7.4) 용액 형태로 제공되며 보존제 없음. -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B4 |
| Immunogen | HEY1 (NP_036390, 181 a.a. approximately 288 a.a) full-length recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG SAHPEAPALR APPSGSFGPV LPVVTSASKL SLPLLSSVAS LSAFPFSFGS FHLLSPNALS PSAPTQAA
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch Signaling Pathway protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HEY1 functions as a downstream effector of Notch signaling and may be required for cardiovascular development.
It acts as a transcriptional repressor binding preferentially to the canonical E-box sequence (5'-CACGTG-3').
HEY1 represses transcription by cardiac transcriptional activators GATA4 and GATA6, and is also expressed during nervous system development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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