Thermo Fisher Scientific HEY1 Monoclonal Antibody (3D1)
HEY1 단백질을 표적으로 하는 Thermo Fisher Scientific의 3D1 클론 단일클론 항체입니다. Western blot 및 ELISA에 사용 가능하며, 인간 반응성 Mouse IgG2a 형식입니다. Notch 신호전달 연구 및 심혈관 발달 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D1 |
| Immunogen | HEY1 (NP_036390, 181 a.a. approximately 288 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG SAHPEAPALR APPSGSFGPV LPVVTSASKL SLPLLSSVAS LSAFPFSFGS FHLLSPNALS PSAPTQAA
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch Signaling Pathway protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HEY1 acts as a downstream effector of Notch signaling and may be required for cardiovascular development.
It functions as a transcriptional repressor binding preferentially to the canonical E-box sequence 5'-CACGTG-3'.
HEY1 represses transcription by cardiac transcriptional activators GATA4 and GATA6 and is reported to be expressed during nervous system development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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