Thermo Fisher Scientific HEY1 Monoclonal Antibody (1F11)
HEY1 단백질을 인식하는 Mouse monoclonal antibody(클론 1F11)로 Western blot, ICC/IF, ELISA에 사용 가능. HEY1 단백질 연구 및 Notch 신호전달 경로 분석에 적합. Affinity chromatography로 정제된 액상 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F11 |
| Immunogen | HEY1 (NP_036390, 121–220 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHAGLGHIPW GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch Signaling Pathway protein. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HEY1 acts as a transcriptional repressor binding preferentially to the canonical E-box sequence (5’-CACGTG-3’). It represses transcription by cardiac transcriptional activators GATA4 and GATA6 and is involved in cardiovascular and nervous system development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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