Thermo Fisher Scientific Carboxypeptidase A1 Polyclonal Antibody
Thermo Fisher Scientific의 Carboxypeptidase A1 Polyclonal Antibody는 인간 CPA1 단백질을 인식하는 염소 유래 IgG 항체입니다. Western blot, IP, Neutralization에 적합하며, 고순도 항원 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
| Neutralization (Neu) | 1.7 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Carboxypeptidase A1 (CPA1) Lys17–Tyr419 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609404 |
Product Specific Information
In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse CPA1 is observed and less than 10% cross-reactivity with recombinant human CPB1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Carboxypeptidase A1 (CPA1), also known as CPA, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation. CPA1 may also participate in zymogen inhibition, regulating enzyme activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting potential involvement in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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