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Thermo Fisher Scientific CD122 Monoclonal Antibody (5H4), Biotin, eBioscience
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Thermo Fisher Scientific

Thermo Fisher Scientific CD122 Monoclonal Antibody (5H4), Biotin, eBioscience

상품 한눈에 보기

마우스 CD122(IL-2 수용체 베타 체인)에 특이적인 단클론 항체로 NK 및 T 세포 표지에 사용. Biotin 결합 형태로 Flow Cytometry에 최적화. 0.25 µg/test 농도로 사용 권장. 4°C 암조건 보관, 동결 금지.

카탈로그번호
13-1221-8x (2개 옵션)
브랜드
Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

카탈로그

2개 옵션
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마지막 업데이트 2025. 08. 04. 오전 04:13
Thermo Fisher Scientific 13-1221-82 CD122 Monoclonal Antibody (5H4), Biotin, eBioscience 100 ug pk판매 단위 pk ·
재고 확인 필요
335,300원VAT 포함 368,830원
Thermo Fisher Scientific 13-1221-81 CD122 Monoclonal Antibody (5H4), Biotin, eBioscience 50 ug pk판매 단위 pk ·
재고 확인 필요
303,600원VAT 포함 333,960원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific CD122 Monoclonal Antibody (5H4), Biotin, eBioscience

Thermo Fisher Scientific CD122 Monoclonal Antibody (5H4), Biotin, eBioscience

Applications

Product Specifications

항목 내용
Species Reactivity Mouse
Published Species Mouse
Host / Isotype Rat / IgG2a, kappa
Recommended Isotype Control Rat IgG2a kappa Isotype Control (eBR2a), Biotin, eBioscience™
Class Monoclonal
Type Antibody
Clone 5H4
Conjugate Biotin
Form Liquid
Concentration 0.5 mg/mL
Purification Affinity chromatography
Storage Buffer PBS, pH 7.2
Contains 0.09% sodium azide
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_466576
Filtration 0.2 µm post-manufacturing filtered

Additional Formats

Product Specific Information

The 5H4 antibody reacts with mouse CD122, the 90–110 kDa interleukin-2 receptor beta chain. CD122 is expressed by NK cells and some T cells in the periphery and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high-affinity IL-2 receptor.
Binding of IL-2 to CD122 is not inhibited by the 5H4 antibody.

Applications Reported:
The 5H4 antibody has been reported for use in flow cytometric analysis.

Applications Tested:
The 5H4 antibody has been tested by flow cytometric analysis of resting and activated mouse splenocytes. Recommended usage is ≤0.25 µg per test (defined as the amount of antibody that stains a cell sample in 100 µL final volume). Cell number may vary from 10⁵ to 10⁸ cells/test. Antibody titration is recommended for optimal assay performance.

Target Information

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:

  • Low affinity form: α subunit monomer, not involved in signal transduction
  • Intermediate affinity form: α/β heterodimer
  • High affinity form: α/β/γ heterotrimer

Both intermediate and high affinity forms participate in receptor-mediated endocytosis and mitogenic signal transduction.
The CD122 gene encodes the beta subunit, a type I membrane protein.
Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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