Thermo Fisher Scientific TPH2 Monoclonal Antibody (CL2990)
TPH2 단백질을 표적으로 하는 Mouse monoclonal antibody(CL2990). 인간, 마우스, 랫트 시료에 반응하며 IHC(P)에서 1:1,000–1:2,500 희석으로 사용 가능. Protein A로 정제된 액상형 항체로, PBS/glycerol buffer에 보존되어 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL2990 |
| Immunogen | Recombinant protein corresponding to human TPH2 (amino acids 438–489) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS (pH 7.2) with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2848913 |
Product Specific Information
Immunogen sequence:
SITRPFSVYF NPYTQSIEIL KDTRSIENVV QDLRSDLNTV CDALNKMNQY LG
Target Information
Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate-limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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