Thermo Fisher Scientific Glutamine Synthetase Monoclonal Antibody (CL2999)
Glutamine Synthetase 단백질을 인식하는 Mouse monoclonal antibody(CL2999)로, WB 및 IHC(P) 검증 완료. Protein A 정제, PBS/glycerol buffer 보존. Human, Mouse, Rat 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL2999 |
| Immunogen | Recombinant protein corresponding to Human Glutamine Synthetase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2848910 |
Product Specific Information
Immunogen sequence:
LQSEGSNSDM YLVPAAMFRD PFRKDPNKLV LCEVFKYNRR PAETNLRHTC KRIMDMVSNQ HPWFGMEQEY TLMGTDGHPF GWPSNGFPGP QGPYYCGVGA DRAYGRDIVE AHYRACLYAG VKIAGTNAEV MPAQWEFQIG P
Target Information
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen flow, serving as both a nitrogen donor and acceptor. It also regulates neurotransmitter glutamate metabolism. Due to its multiple functions, GS activity and synthesis are tightly regulated, including by adenylylation. Activity decreases in Alzheimer’s disease brain cortex and under glucose deprivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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