
Thermo Fisher Scientific KCNK3 Monoclonal Antibody (N374/48), PE
KCNK3 단백질을 인식하는 Mouse 모노클로날 항체로, PE 형광 표지된 제품입니다. Western blot, IHC, ICC/IF에 사용 가능하며 Human, Mouse, Rat 시료에 반응합니다. 고순도 Protein G 정제, 무보존제, 4°C 보관.
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Thermo Fisher Scientific KCNK3 Monoclonal Antibody (N374/48), PE
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N374/48 |
| Immunogen | Fusion protein amino acids 251–411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932158 |
Additional Formats
- Unconjugated: MA5-27677
- APC: MA5-45701
- FITC: MA5-45702
- PerCP: MA5-45703
- Custom conjugation available upon request
Product Specific Information
- Mouse: 96% identity (156/161 amino acids identical)
- Human: 76% identity (163/161 amino acids identical)
- <30% identity with TASK3
- 1 µg/mL of MA5-45704 detects TASK1 Potassium Channel in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as secondary antibody
- Detects approximately 50 kDa
- Does not cross-react with TASK3
- Formerly sold as clone S374-48
Target Information
KCNK3 encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The gene product forms an outwardly rectifying channel sensitive to extracellular pH and inhibited by acidification. It is also referred to as an acid-sensitive potassium channel and is activated by anesthetics such as halothane and isoflurane. Although three transcripts are detected in northern blots, sequence confirmation for transcript variants is not yet available.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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