Thermo Fisher Scientific Phospho-S6 Ribosomal Protein (Ser235, Ser236) Recombinant Rabbit Monoclonal Antibody (S6S235S236-R3A2), PE
Phospho-S6 Ribosomal Protein (Ser235/236)에 특이적인 재조합 토끼 단클론 항체로, PE 형광 표지되어 Flow Cytometry에 최적화됨. 인간 및 생쥐 반응성. Protein A/G 정제, PBS+BSA 완충액, 4°C 보관.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | S6S235S236-R3A2 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser235/236 of human phospho S6 Ribosomal Protein |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897174 |
Additional Formats
Target Information
Ribosomes are organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and about 80 structurally distinct proteins. The S6 ribosomal protein is a component of the 40S subunit and belongs to the S6E family. It serves as a major substrate for ribosomal protein kinases, with phosphorylation occurring at several C-terminal serine residues (including Ser235/236). Phosphorylation is induced by various stimuli such as growth factors, tumor promoters, and mitogens, while dephosphorylation occurs during growth arrest. This protein plays a role in regulating cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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