Thermo Fisher Scientific Phospho-S6 Ribosomal Protein (Ser235, Ser236) Recombinant Rabbit Monoclonal Antibody (S6S235S236-R3A2), APC
APC 형광으로 표지된 재조합 rabbit monoclonal 항체로, Ser235/236 인산화된 S6 ribosomal protein을 검출합니다. Flow cytometry에 최적화되어 있으며, Human 및 Mouse 시료에 반응합니다. 단백질 합성 및 세포 성장 조절 연구에 유용합니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | S6S235S236-R3A2 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser235/236 of human phospho S6 Ribosomal Protein |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897176 |
Additional Formats
- Unconjugated: MA5-36931
- FITC: MA5-36933
- PE: MA5-36932
- Custom conjugation available upon request
Target Information
Ribosomes are organelles that catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and about 80 distinct proteins. The encoded cytoplasmic ribosomal protein is part of the 40S subunit and belongs to the S6E family. It serves as a major substrate for multiple protein kinases that phosphorylate five C-terminal serine residues. Phosphorylation is induced by various stimuli such as growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs during growth arrest. This protein is implicated in the control of cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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