Thermo Fisher Scientific AOC3 Recombinant Mouse Monoclonal Antibody (2D10)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (IHC)

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2D10

Immunogen

Affinity purified VAP-1 from tonsil stroma of human origin. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AOC3,uniProtId:Q16853-1,ncbiNodeId:9606,antigenRange:1-763,antigenLength:763,antigenImageFileName:MA5-47812_AOC3_Q16853-1_House_mouse.svg,antigenImageFileNamePDP:MA5-47812_AOC3_Q16853-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074259

Product Specific Information

Specificity: Recognises human Vascular Adhesion Protein-1 (VAP-1), a glycosylated homodimeric membrane protein consisting of two 90 kDa subunits connected by disulfide bonds. 2D10 is a conformational specific antibody which recognizes an epitope present only in the dimeric form of VAP-1. Elevated soluble VAP-1 serum- levels have been described in several inflammatory- diseases as well as colorectal cancer.

Target Information

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.