Thermo Fisher Scientific CD19 Recombinant Mouse Monoclonal Antibody (FMC63)
사람 CD19 단백질을 인식하는 마우스 유래 재조합 단일클론 항체. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능. Protein A로 정제된 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| Functional Assay (Functional) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FMC63 |
| Immunogen | Human prolymphocytic leukaemia cell line JVM3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody is specific for human CD19, a 95 kDa protein expressed in the B-lymphocyte lineage.
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also appear on certain myeloid leukemia cells. CD19 functions as a key regulator of normal and malignant B cell proliferation and is expressed in all B cell precursor leukemias. It acts as a signal-amplifying coreceptor for the B cell receptor (BCR) and can signal independently of BCR co-ligation. Mutations in CD19 lead to hypogammaglobulinemia, while overexpression results in B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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