Thermo Fisher Scientific ANAPC11 Monoclonal Antibody (OTI1B11), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

Together with the cullin protein ANAPC2, ANAPC11 forms the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase controlling progression through mitosis and the G1 phase.
The APC/C complex mediates ubiquitination and degradation of target proteins, primarily forming Lys-11-linked polyubiquitin chains and, to a lesser extent, Lys-48- and Lys-63-linked chains.
May recruit E2 ubiquitin-conjugating enzymes to the complex. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.