Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), PerCP
인간 CD45 항원을 인식하는 마우스 단클론 항체로, PerCP로 결합되어 유세포분석(Flow Cytometry)에 적합. 모든 혈액세포에서 CD45 발현 검출 가능. PBS/BSA 완충액에 보존되며 4°C 암소 보관. 연구용으로만 사용.
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Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), PerCP
Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL/10^6 cells
Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Immunogen | Human peripheral blood mononuclear cells |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898645 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of all alternative forms of human CD45 antigen (Leukocyte Common Antigen), a 180–220 kDa single-chain type I transmembrane protein expressed at high levels on all cells of hematopoietic origin, except erythrocytes and platelets.
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed ubiquitously in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes.
It is absent on non-hematopoietic cell lines and tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, regulating Src-family kinases and JAK kinases, and playing roles in integrin-mediated signaling, apoptosis, and immunological function modulation.
Multiple isoforms exist due to alternative splicing, differing in extracellular domains but sharing identical transmembrane and cytoplasmic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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