Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), APC-Cyanine7
인간 CD45 항원을 인식하는 마우스 단클론 항체로, APC-Cyanine7 형광 표지 형식입니다. 유세포 분석(Flow Cytometry)에 적합하며, PBS + 0.2% BSA 완충액에 보관됩니다. 4°C 암소 보관, 동결 금지. 연구용으로만 사용 가능합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 4 µL/10⁶ cells
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Immunogen | Human peripheral blood mononuclear cells |
| Conjugate | APC-Cyanine7 |
| Excitation / Emission Max | 653 / 782 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898643 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of all alternative forms of human CD45 antigen (Leukocyte Common Antigen), a 180–220 kDa single-chain type I transmembrane protein expressed at high levels on all cells of hematopoietic origin, except erythrocytes and platelets.
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed in all nucleated hematopoietic cells, comprising approximately 10% of surface proteins in lymphocytes. It is absent in non-hematopoietic cell lines and tissues. CD45 plays a critical role in lymphocyte development and antigen signaling, regulating Src-family kinases and cytokine receptor pathways. Multiple isoforms exist due to alternative splicing, differing in extracellular domains but sharing identical transmembrane and cytoplasmic domains. CD45 is essential for T- and B-cell receptor signaling, cytokine regulation, and integrin-mediated survival signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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