Thermo Fisher Scientific KLRG1 Monoclonal Antibody (2F1), Biotin, eBioscience
Mouse KLRG1 단백질을 인식하는 2F1 클론의 Biotin 결합 단일클론 항체입니다. Flow cytometry 분석에 최적화되어 있으며, 0.06 µg/test로 사용 가능합니다. Syrian hamster IgG 아이소타입, PBS buffer, 4°C 보관 조건을 갖습니다.
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Thermo Fisher Scientific KLRG1 Monoclonal Antibody (2F1), Biotin, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry | 0.06 µg/test | View 25 publications |
| Functional Assay | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Syrian hamster / IgG |
| Recommended Isotype Control | Syrian Hamster IgG Isotype Control, Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F1 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_466770 |
| Filtration | 0.2 µm post-manufacturing filtered |
Available Formats
- Alexa Fluor 488
- Alexa Fluor 532
- Alexa Fluor 561
- Alexa Fluor 647
- APC
- APC-eFluor 780
- Brilliant UV 395 / 496 / 563 / 615
- Brilliant Violet 421 / 480 / 605 / 711
- eFluor 450 / 506
- FITC
- Functional Grade
- Pacific Orange
- PE / PE-Cyanine5 / PE-Cyanine5.5 / PE-Cyanine7 / PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436 / 600 / 645 / 702 / 780
- Request custom conjugation
Product Specific Information
This 2F1 monoclonal antibody reacts with mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA).
KLRG1 is a homodimer of glycosylated 30–38 kDa subunits containing a cytoplasmic ITIM motif. It is expressed on approximately one-third of mouse NK cells and a subset of T cells.
MHC class I molecules regulate KLRG1 via interactions with Ly49 molecules and SHP-1 signaling.
Applications Reported: Use in flow cytometric analysis.
Applications Tested: Tested by flow cytometric analysis of mouse splenocytes at ≤0.06 µg/test (100 µL final volume). Optimal titration recommended for specific assays.
Target Information
KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric lectin-like type 2 transmembrane receptor containing ITIM motifs that interact with SHP-1 phosphatase.
It functions as an inhibitory receptor expressed on NK cells and certain T cells, involved in tumor and virus-infected cell lysis and immune regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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