Thermo Fisher Scientific ATG10 Polyclonal Antibody
ATG10 단백질을 인식하는 Thermo Fisher Scientific의 sheep 유래 polyclonal antibody. Western blot과 Immunohistochemistry에 사용 가능. 자가포식 관련 연구용으로 적합하며, 동결건조 형태로 제공되어 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:200–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from human ATG10 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: ATG10.
Target Information
ATG10 is involved in autophagy, a process for the bulk degradation of cytosolic compartments by lysosomes/vacuoles. The formation of autophagosomes requires dynamic membrane rearrangement and two ubiquitin-like modifications: conjugation of APG12p and modification of MAP-LC3 to a membrane-bound form.
APG10 functions as an E2-like enzyme essential for autophagosome formation, mediating ATG12–ATG5 conjugation and MAP-LC3 (MAP1LC3A) modification.
ATG10 is ubiquitously expressed, and the human APG10L gene is localized on chromosome 5q14.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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