Thermo Fisher Scientific MCMBP Polyclonal Antibody
MCMBP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA에 사용 가능. Human 및 Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
- 카탈로그번호
- PA549723
- 판매단위
- pk
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Thermo Fisher Scientific MCMBP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
| ELISA | 1:2,000–1:5,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 176–190 of human minichromosome maintenance complex binding protein (MCMBP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2635176 |
Product Specific Information
This antibody detects endogenous levels of total MCMBP protein.
Target Information
MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the phosphorylation of threonine and tyrosine residues in the Thr-Glu-Tyr sequence of MAP kinases, activating ERK1 and ERK2. MEK2 (MAPKK2) also activates ERK1/2 by dual phosphorylation within the TEY motif. MEK1 and MEK2 are activated by phosphorylation at serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, providing a negative feedback mechanism that suppresses MEK1 activation.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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