Thermo Fisher Scientific MMP27 Polyclonal Antibody
MMP27 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ELISA에 적합합니다. 인간 및 마우스 반응성, Rabbit IgG 호스트, 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1:1,000–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 440–452 of human matrix metallopeptidase 27 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2635177 |
Product Specific Information
The antibody detects endogenous levels of total MMP27 protein.
Target Information
Metalloproteinases (MMPs) are a family of proteins involved in the breakdown of the extracellular matrix during normal cellular events such as reproduction, tissue remodeling, and embryonic development. MMPs are crucial in tumor invasion and metastasis formation due to their ability to degrade extracellular matrix proteins like fibronectin, laminin, gelatins, and collagen.
MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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