Thermo Fisher Scientific CD19 Chimeric Recombinant Rabbit Monoclonal Antibody (CAT-13.1E10)
CD19 단백질을 인식하는 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. ICC/IF, 유세포분석, 기능적 분석에 사용 가능하며, Protein A로 정제된 액상 형태입니다. B세포 발달 및 활성 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 1:100 |
| Functional Assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CAT-13.1E10 |
| Immunogen | This antibody was raised by immunising mice against CD19. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074700 |
Product Specific Information
Specificity: CAT-13.1E10 antibody recognises CD19, a transmembrane glycoprotein that regulates B lymphocyte development, activation, and differentiation.
Target Information
CD19 is a member of the immunoglobulin superfamily and has two Ig-like domains. It is expressed on 100% of peripheral B cells defined by kappa or lambda light chain expression. CD19 is also found on certain myeloid leukemia cells, particularly of monocytic lineage.
It functions as a key regulator of B cell proliferation and differentiation, acting as a signal-amplifying coreceptor for the B cell receptor (BCR). Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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