Thermo Fisher Scientific Caveolin 2 Polyclonal Antibody
Thermo Fisher Scientific의 Caveolin 2 Polyclonal Antibody는 mouse 및 rat 시료에서 caveolin-2 단백질을 검출하는 고특이성 항체입니다. Western blot과 IP에 적합하며, caveolin-1 및 -3과 교차반응하지 않습니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 2 publications |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues M(1) G L E T E K A D V Q L F M A D D A Y(19) C of rat CAV2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2244214 |
Product Specific Information
PA1-065 detects caveolin-2 from rat and mouse tissues. This antibody does not detect caveolin-1 or -3.
It has been successfully used in Western blot and immunoprecipitation procedures.
By Western blot, this antibody detects a ~21 kDa protein representing caveolin-2 from rat heart homogenate.
The immunogen is a synthetic peptide corresponding to residues M(1) G L E T E K A D V Q L F M A D D A Y(19) C of rat CAV2.
This sequence is completely conserved in mouse and approximately 90% conserved in human caveolin-2.
The immunizing peptide (Cat. # PEP-080) is available for use in neutralization and control experiments.
Target Information
Caveolae are specialized plasma membrane domains involved in the sequestration of lipid and protein molecules.
They play key roles in lipid metabolism, growth regulation, signal transduction, and apoptosis.
Caveolin interacts with and regulates heterotrimeric G-proteins.
Three members of the caveolin family encode 21–24 kDa integral membrane proteins that form the major structural component of caveolae.
Caveolin-2 is expressed in fibroblasts, adipocytes, smooth and skeletal muscle, and endothelial cells.
Caveolin-1 shows similar expression patterns, while caveolin-3 is mainly found in muscle tissue.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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