Thermo Fisher Scientific CD3e Monoclonal Antibody (145-2C11), FITC
마우스 CD3ε 항원을 인식하는 Armenian hamster 유래 단클론 항체. FITC 형광 표지로 유세포분석(Flow Cytometry)에 적합. 498/517 nm 여기/방출 특성. 액상 형태로 제공되며 4°C 암소 보관. 연구용으로만 사용.
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Applications
- Flow Cytometry (Flow): 1–3 µg/mL
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 145-2C11 |
| Immunogen | Mouse BM10-37 cytotoxic T lymphocytes |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155980 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of murine CD3 (epsilon subunit).
It is commonly used as a phenotypic marker for murine T cells.
Target Information
The CD3 subunit complex is crucial for transducing antigen-recognition signals into T cells and regulating TCR complex expression.
CD3 subunits (gamma, delta, epsilon, zeta) are part of the immunoglobulin superfamily and encoded by genes on chromosome 11.
They associate with cytoplasmic signal transduction molecules via tyrosine-based motifs.
CD3 antigens are present on 68–82% of normal peripheral blood lymphocytes and 65–85% of thymocytes, but not on B or NK cells.
Defects in CD3 genes are associated with CD3 immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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