Thermo Fisher Scientific QSER1 Polyclonal Antibody
Human QSER1 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. PBS/glycerol buffer에 보존되어 안정적이며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human QSER1. Recombinant protein control fragment (Product # RP-88726) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646193 |
Product Specific Information
Immunogen sequence:
QQHIETPGQN IPTKVTSAVV GPSHEVQEQS SGPFKKQSAT NLESEEDSEA PVDSTLNNNR NQEFVSSSRS ISGESATSES EFTLGGDDSG VSMNPARSAL ALLAMAQSGD AVSVKIEEEN QDLMHFNLQK KRAKGKGQVK
Highest antigen sequence identity to the following orthologs:
- Mouse: 66%
- Rat: 66%
Target Information
QSER1 (glutamine and serine-rich protein 1) is a 1,735 amino acid protein that is phosphorylated upon DNA damage, probably by Atm or ATR.
A single nucleotide polymorphism (SNP) between QSER1 and PRRG4 on chromosome 11 has been suspected of association with Parkinson disease.
QSER1 exists as two alternatively spliced isoforms and is conserved in multiple species including chimpanzee, canine, bovine, mouse, rat, chicken, and zebrafish.
It maps to human chromosome 11p13, which contains approximately 135 million base pairs and around 1,400 genes, representing about 4% of human genomic DNA.
Chromosome 11 is known for its high gene and disease association density, including links to Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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