Thermo Fisher Scientific TRIM21 Polyclonal Antibody
Human TRIM21 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. PBS/glycerol buffer에 보관하며 연구용으로 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:5,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRIM21. Recombinant protein control fragment (Product #RP-88581) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648914 |
Product Specific Information
Immunogen sequence:
LEKDEREQLR ILGEKEAKLA QQSQALQELI SELDRRCHSS
Highest antigen sequence identity to the following orthologs:
- Mouse: 70%
- Rat: 75%
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (a RING, a B-box type 1, and a B-box type 2) and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus and interacts with autoantigens in patients with Sjögren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described, but the full-length nature of only one has been determined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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