Thermo Fisher Scientific CYSLTR2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 10 µg/mL

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Gorilla (100%); Gibbon (95%); Marmoset (80%)
• For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
• After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium.
The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.