Thermo Fisher Scientific CXCR2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 5–10 µg/mL

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Chimpanzee, Gibbon (100%); Gorilla (94%); Marmoset (88%)
• For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
  After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

CXCR2 is a receptor for interleukin-8 (IL-8), a potent neutrophil chemotactic factor.
It belongs to the GPCR family. Binding of IL-8 to CXCR2 activates neutrophils through a G-protein-mediated phosphatidylinositol-calcium second messenger system.
CXCR2 binds IL-8, GRO/MGSA, and NAP-2 with high affinity and is expressed in various tissues including placenta and thymus.

For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.

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