Thermo Fisher Scientific CXCR2 Polyclonal Antibody
CXCR2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P)에서 5–10 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 장기 보관은 -20°C에서 권장.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from N-terminal extracellular domain of human CXCR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550178 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gibbon (100%); Gorilla (94%); Marmoset (88%) - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
CXCR2 is a receptor for interleukin-8 (IL-8), a potent neutrophil chemotactic factor.
It belongs to the GPCR family. Binding of IL-8 to CXCR2 activates neutrophils through a G-protein-mediated phosphatidylinositol-calcium second messenger system.
CXCR2 binds IL-8, GRO/MGSA, and NAP-2 with high affinity and is expressed in various tissues including placenta and thymus.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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