Thermo Fisher Scientific Plasminogen Monoclonal Antibody (8F11)
인간 plasminogen을 검출하는 mouse monoclonal antibody (clone 8F11). IHC, ELISA, Affinity Purification 등 다양한 응용에 적합. 높은 순도와 8.3 mg/mL 농도, 액상 형태로 제공되며 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Plasminogen Monoclonal Antibody (8F11)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| ELISA | Assay-dependent |
| Affinity Purification (AP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8F11 |
| Immunogen | Purified, full length, native, human plasminogen protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.3 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_560667 |
Product Specific Information
MA1-20082 detects plasminogen in human samples.
Target Information
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain with a molecular weight of approximately 88.5 kDa. The plasma concentration typically ranges from 70 to 200 mg/L.
Plasminogen is activated by tissue-plasminogen activator, urokinase, and streptokinase to form plasmin through cleavage and release of the preactivation peptide.
Plasmin comprises a heavy (A-) chain containing five kringles and a light (B-) chain with the active site. It is a trypsin-like protease that acts on fibrin, with fibrin-binding sites on the kringles.
Plasmin plays an essential role in fibrinolysis; congenital defects can lead to recurring thrombosis, thrombophlebitis, and pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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