Thermo Fisher Scientific Plasminogen Monoclonal Antibody (9D8)
인간 plasminogen을 검출하는 mouse monoclonal antibody로 IHC, ELISA, Affinity Purification에 사용 가능. 2 mg/mL 농도의 액상 형태이며 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Affinity Purification (AP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9D8 |
| Immunogen | Purified, full length, native, human plasminogen protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_560665 |
Product Specific Information
MA1-20080 detects plasminogen in human samples.
Target Information
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70–200 mg/L.
Plasminogen is activated by tissue-plasminogen activator, urokinase, and streptokinase to form plasmin. Activation results from the cleavage and release of the preactivation peptide.
Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles.
Plasmin is essential for fibrinolysis, and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis, and pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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