Thermo Fisher Scientific Plasminogen Monoclonal Antibody (9E7)
인간 플라스미노겐을 인식하는 마우스 단클론 항체로, IHC, ELISA, Affinity Purification 등 다양한 분석에 적합합니다. 고농도 액상 형태(8.7 mg/mL)로 제공되며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| ELISA | Assay-dependent |
| Affinity Purification (AP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9E7 |
| Immunogen | Purified, full length, native, human plasminogen protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.7 mg/mL |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Wet ice |
| RRID | AB_560664 |
Product Specific Information
MA1-20079 detects plasminogen in human samples.
Target Information
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70–200 mg/L.
Plasminogen is activated by tissue-plasminogen activator, urokinase, and streptokinase to form plasmin. Activation results from the cleavage and release of the preactivation peptide.
Plasmin consists of a heavy (A-) chain containing 5 kringles and a light (B-) chain with the active site. It is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles.
Plasmin is essential for fibrinolysis, and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis, and pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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