Thermo Fisher Scientific CD52 Recombinant Rat Monoclonal Antibody (YTH 34.5-G2b (Campath-1G))
CD52 항원을 인식하는 랫트 유래 재조합 단클론 항체로 다양한 면역분석(WB, IHC, Flow, ELISA 등)에 사용 가능. 인간 및 영장류 반응성. HEK293 발현 시스템 기반, Protein A 정제. 연구용으로 면역세포 표면 CD52 검출 및 기능 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Functional Assay | Assay-dependent |
| Cytotoxicity Assay (CT) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Rhesus monkey |
| Host / Isotype | Rat / IgG2b, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | YTH 34.5-G2b (Campath-1G) |
| Immunogen | Human peripheral mononuclear cells enriched for T-cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
Human CD52 antigen, also known as CAMPATH-1, is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes, and macrophages. It is also expressed by most lymphoid-derived malignancies, although expression on myeloma cells is variable.
Target Information
CD52 (CAMPATH-1 antigen) is a glycoprotein expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It plays a role in immune response regulation and is studied as a therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody used to treat these conditions by depleting CD52-expressing immune cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-51888_CD52_P31358-1_Rat.svg, MA5-51888_CD52_P31358-1_Rat_PDP.jpeg)
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