Thermo Fisher Scientific HSD17B10 Monoclonal Antibody (OTI3B5), TrueMAB
Human HSD17B10 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합. Lyophilized 형태이며 Protein G로 정제됨. PBS buffer(8% trehalose, 무보존제)로 구성되어 -20°C 보관. Alzheimer’s disease 및 MHBD 관련 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B5 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human HSD17B10 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The HSD17B10 gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a mitochondrial enzyme belonging to the short-chain dehydrogenase/reductase superfamily.
It catalyzes oxidation of fatty acids, alcohols, and steroids.
Mutations cause 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD) and have been associated with Alzheimer’s disease.
Several alternatively spliced transcript variants exist, with two full-length forms identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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