Thermo Fisher Scientific PSMA7 Monoclonal Antibody (OTI8F9), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

PSMA7 is a component of the 20S core proteasome complex involved in proteolytic degradation of intracellular proteins.
This complex plays essential roles in maintaining protein homeostasis by removing misfolded or damaged proteins and regulating the degradation of ubiquitinated proteins.
The 26S proteasome (20S core + 19S regulatory particles) participates in ATP-dependent degradation, while the 20S complex associated with PA200 or PA28 mediates ubiquitin-independent pathways such as spermatogenesis and MHC class I antigen processing.
PSMA7 also inhibits HIF-1A transactivation under normoxic and hypoxic conditions, promotes its degradation, and plays a role in hepatitis C virus translation and androgen receptor nuclear translocation.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.