Thermo Fisher Scientific PSMA7 Monoclonal Antibody (OTI3F11), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

PSMA7 is a component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.
This complex plays essential roles by associating with different regulatory particles.

• Forms the 26S proteasome with two 19S regulatory particles for ATP-dependent degradation of ubiquitinated proteins.
• Plays a key role in maintaining protein homeostasis by removing misfolded or damaged proteins.
• Mediates ubiquitin-independent degradation when associated with PA200 or PA28 complexes.
• Involved in spermatogenesis and generation of MHC class I-presented peptides.
• Inhibits HIF-1A transactivation and enhances HIF-1A degradation under hypoxic conditions.
• Plays a role in hepatitis C virus translation and androgen receptor nuclear translocation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.