Thermo Fisher Scientific CAF1 p60 Monoclonal Antibody (SS 53)
CAF-1 p60 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, IP 등에 사용 가능. 인간 시료에 반응하며, 비결합형 액상 형태. 염색체 상태 유지 및 DNA 복제 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: 1:10–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SS 53 |
| Immunogen | Recombinant human CAF-1p60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_568475 |
Product Specific Information
Suggested positive control: antigen standard for CHAF1B (transient overexpression lysate).
Target Information
Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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