Thermo Fisher Scientific TLR7 Polyclonal Antibody
TLR7 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB 및 IHC(P) 실험에 적합합니다. 인간에 반응하며, 예측 반응종에는 마우스, 랫트, 개, 고양이 등이 포함됩니다. 항원 친화 크로마토그래피로 정제된 액상 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human TLR7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792632 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (81%), Rat (84%), Dog (82%), Cat (84%), Pig (81%), Sheep (85%), Rhesus Monkey (96%), Chimpanzee (100%), Bovine (86%).
- Positive Control: 293T transfected recombinant TLR7 protein.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TLR7 is a highly conserved membrane protein of the Toll-like receptor (TLR) family, containing 27 leucine-rich repeats (LRR) and a TIR domain. It plays a key role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses such as influenza and vesicular stomatitis virus (VSV). It is predominantly expressed in lung, placenta, and spleen, and located near TLR8. TLR7 acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion, and inflammatory response. It recognizes pathogen-associated molecular patterns (PAMPs) and mediates cytokine production essential for effective immunity.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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